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ShortCut: What are the general rules of regulation?

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ShortCut: What are the general rules of regulation?

The general rules of regulation indicate a simple and basic logic in life and evolution considered the equilibrium in the environment. In other words, with these rules, we can predict the future of potential species, classification comprising related organisms that share common characteristics and are capable of interbreeding, in a random habitat. Furthermore, we can discern how any course of action against indigenous species detrimentally might affect nature and applied fields.

“Like the double-negative logic of enzyme induction, the logic of negative feedback in biosynthetic pathways also made great biological sense: when the end-product of a pathway is abundant, cells do not waste energy making it or any intermediates; but when the concentration is low, the synthetic machinery is not inhibited, and the needed product is synthesized(1).”

“These pioneering studies of bacteria revealed four basic ways that one molecule can affect the abundance of another molecule. They constitute a set of general rules and a logic of regulation that, as we shall see, govern all sorts of processes in other species(1).”

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Figure - 70.1

General Rules of Regulation

A, B, and C imply any conceivable variable in a food chain.

1) Positive Regulation

A positively regulates the abundance or activity of B

2) Negative Regulation

A negatively regulates the abundance or activity of B

3) Double-negative Logic

A negatively regulates B, which negatively regulates C; A increases the abundance of C through double-negative logic

4) Feedback Regulation

The accumulation of C feeds back to negatively regulate A and the production of B and C

References

(1) Carroll, Sean B. "General Rules of Regulation." The Serengeti Rules: The Quest to Discover How Life Works and Why It Matters. New Jersey: Princeton University Press, 2017. 68. Print.

Figure - 70.1 https://3c1703fe8d.site.internapcdn.net/newman/csz/news/800/2017/heliumionsre.png